Isomorphic stated in June of 2002 that they were "working on a .NET-native version of the ISC server-side framework".

http://www.smartclient.com/technology/Isomorphic_SmartClient_Tech_Brief.pdf

I could really use this myself and it think it would open the floodgates from the .NET world. Let's vote this up!

Any word on the status of this?